严重心律失常是心肌梗塞的主要致死原因之一。本例为急性广泛前壁心肌梗塞并发室壁瘤,后期有严重室性、室上性心律失常。在多种常用抗心律失常药物治疗无效以后,试用较大剂量氯卡胺,同时应用血管扩张剂,成功地控制了心律失常。现报告如下。患者,男,42岁,因发作性胸痛3小时于1986年12月7日急诊入院。心电图提示急性广泛前壁心肌梗塞。发病后12小时 CPK 达峰值2266u/L,24小 Serious arrhythmia is one of the leading causes of death from myocardial infarction. This case of acute extensive anterior myocardial infarction complicated by aneurysm, late severe intraventricular arrhythmias. In a variety of commonly used anti-arrhythmic drug treatment fails, the trial of larger doses of clofaamide, at the same time the application of vasodilators, successful control of cardiac arrhythmias. The report is as follows. The patient, male, 42 years old, was admitted to the emergency department on December 7, 1986 due to a three-hour episode of chest pain. ECG prompts acute extensive anterior myocardial infarction. 12 hours after onset CPK peak 2266u / L, 24 small