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对睡眠呼吸暂停综合征(SAS)的治疗药物有多种,但无肯定结果。本文报告对20例SAS患者中短期应用乙酰唑胺(acetazolamide)的疗效及夜间持续睡眠多道生理仪(PSG)监测结果。方法:研究对象为20例男性患者,其中主诉白天过度嗜睡(睡眠呼吸暂停伴过度嗜睡综合征)14例,主诉失眠(睡眠呼吸暂停综合征)6例,平均54.6岁。SAS诊断按Guilleminault等的定义,在7小时夜间睡眠中,在NREM期、REM期出现至少持续10秒钟以上的换气停止(无呼吸)30次以上或每小时呼吸暂停次数(呼吸暂停指数)5次以
There are many treatments for sleep apnea syndrome (SAS), but no positive result. This article reports the efficacy of short-term acetazolamide in 20 patients with SAS and the results of nighttime continuous sleep polysomnography (PSG) monitoring. Methods: The study was performed on 20 male patients. Among them, 14 complained of excessive daytime sleepiness (sleep apnea and excessive sleepiness syndrome) and 6 cases of insomnia (sleep apnea syndrome), with an average of 54.6 years. SAS Diagnostics As defined by Guilleminault et al., During a 7-hour nighttime sleep, there was at least a 10-second ventilation stop (no breathing) in NREM, REM, more than 30 breaths per hour or apnea per hour (apnea index) 5 times