硝基咪唑类药物包括甲硝唑、替硝唑、奥硝唑等,是治疗厌氧菌感染的常用药物。该类药物的第一代产品为甲硝唑,又名灭滴灵,最初被用于治疗滴虫性阴道炎,后发现对口腔内多种厌氧菌感染有效而逐渐应用于口腔疾病的治疗。甲硝唑是一种高效价廉、能杀灭专性厌氧菌的药物,不易引起菌群失调,也不易产生耐药菌株,它与大多数常用的抗生寨无配伍禁忌。部分患者使用甲硝 Nitroimidazole drugs include metronidazole, tinidazole, ornidazole, etc., is commonly used drugs for the treatment of anaerobic infections. The first generation of these drugs is metronidazole, also known as metronidazole, initially used in the treatment of trichomonas vaginitis, and found that the oral cavity a variety of anaerobic infections and gradually applied to the treatment of oral diseases . Metronidazole is a highly effective and inexpensive drug that can kill obligate anaerobic bacteria. It is not easy to cause bacterial imbalance and easy to produce drug-resistant strains. It is incompatible with most commonly used antibiotics. Some patients use metronidazole