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目的:探讨子癎前期患者蛋白尿程度对其围生儿结局的影响。方法:对287例住院分娩的子癎前期患者根据蛋白尿程度进行分组,分别回顾性研究其围生儿结局,比较不同程度蛋白尿患者围生儿结局的差异。结果:随患者蛋白尿的加重,分娩孕周提前,新生儿出生体重明显下降;剖宫产分娩和治疗性引产数升高,而自然分娩数减少;低体重儿发生率、围生儿死亡率、医源性早产率、收住NICU率均明显升高,但新生儿窒息发生率差异无显著性。将所有病例根据分娩孕周分为两组,≥32周分娩者其围生儿结局在不同程度蛋白尿患者各组之间差异显著,而32周之前分娩者其围生儿结局在不同程度蛋白尿之间差异无显著性。结论:随蛋白尿加重,围生儿结局恶化,但较早的早产儿中,孕龄过小是造成围生儿不良结局的另一不利因素,因而终止妊娠应适时。
Objective: To investigate the effect of proteinuria on the perinatal outcome in patients with preeclampsia. Methods: A total of 287 preeclampsia patients were divided into groups based on the degree of proteinuria. The perinatal outcome was retrospectively studied. The differences of perinatal outcomes among different levels of proteinuria were compared. Results: With the exacerbation of proteinuria in patients, the birth gestational age ahead of time, neonatal birth weight decreased significantly; cesarean delivery and therapeutic induced labor increased, while the number of natural delivery decreased; the incidence of low birth weight children, perinatal mortality , Iatrogenic preterm birth rate, NICU admission rate were significantly increased, but the incidence of neonatal asphyxia no significant difference. All cases were divided into two groups according to the gestational age of childbirth. The results of perinatal infants of ≥32 weeks of childbirth differed significantly among groups with different degrees of albuminuria. Before 32 weeks, Urine no significant difference between. CONCLUSION: With the increase of proteinuria, the outcome of perinatal children is deteriorated. However, the earlier gestational age in premature infants is too small. This is another unfavorable factor that causes the poor outcome of perinatal children. Therefore, the termination of pregnancy should be timely.