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探讨准分子激光角膜切削术（ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅＫｃｒａｔｃｔｏｍｙＰＲＫ）后真菌性角膜溃疡的病因、病机及防治策略。方法：对４例（４只眼）ＰＲＫ后（４～１８天）发生的真菌性角膜溃疡患者采用局部及全身抗真菌药物治疗，对药物控制下溃疡恶化者及时采取穿透性角膜移植术（ｐｅｎｅｔｒａｔｉｎｇｋｅｒａｔｏｐｌａｓｔｙ．ＰＫＰ）。结果：所有病例角膜溃疡均得到有效控制，并保留有用视力（０．４～１．０）。结论：ＰＲＫ后早期存在角膜感染的潜在危险性，早期诊断与治疗将直接影响预后；药物治疗无效，角膜溃疡逐步恶化时进行角膜移植手术是唯一有效的治疗措施
To investigate the etiology, pathogenesis and prevention and treatment of fungal corneal ulcer after photorefractive Keratctomy (PRK). Methods: Fungal corneal ulcer occurred in 4 patients (4 eyes) after PRK (4 ~ 18 days). The patients were treated with topical and systemic antifungal drugs. Penetrating keratoplasty penetratingkeratoplasty.PKP). Results: All cases of corneal ulcer were effectively controlled, and retain useful eyesight (0.4 ~ 1.0). Conclusion: There is a potential risk of corneal infection in the early stage after PRK. Early diagnosis and treatment will directly affect the prognosis. Corneal transplantation is the only effective treatment for ineffective drug treatment and gradual deterioration of corneal ulcer