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自发现民间用野生薄荷(简称M.A)终止妊娠以来,作者在1978年研究了M.A的水提取物,发现对大鼠子宫有兴奋作用;1980年又分离出了UM部分。本文主要报导UM部分对大鼠妊娠及其雌激素和性腺激素活性的影响。一、对大鼠妊娠的影响:选用有规则动情周期的雌性大白鼠(150～200g)和有生育力的雄性大鼠合笼,阴道涂片在电镜下发现精虫日为妊娠第一天(D_1)。于妊娠D_1—D_(10)连续皮下注射UM部分5mg/kg或10mg/kg。第10天处死动物时,发现5
Since the discovery of civil termination of pregnancy with wild peppermint (M.A.), the authors studied aqueous extracts of M.A in 1978 and found that they were excited by the rat uterus; in 1980, the UM fraction was isolated. This article mainly reports the UM part of the pregnancy and its estrogen and gonadal hormones activity. First, the impact on rat pregnancy: Selection of regular estrous cycle of female rats (150 ~ 200g) and fertility male rats cage, vaginal smears found under electron microscopy sperm day is the first day of pregnancy (D_1 ). In pregnancy D_1-D_ (10) subcutaneously injected with UM part of the 5mg / kg or 10mg / kg. When the animals were sacrificed on the 10th day, 5 was found