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目的:分析皮肤转移癌的临床病理特征。方法:将患者的病史资料及组织切片进行分析研究。结果:1975年~1996年间36例皮肤转移癌占同期手术病例2.1%,好发于中老年人,患者男女之比为1:2.3;转移位置取决于原发癌的部位及扩散方式;临床表现为结节性32例(89%),炎症性3例,硬皮样性1例;全组中位生存时间9个月,23例在6个月内死亡。结论:皮肤转移癌最常见的来源是内脏癌,且多发生于癌症的晚期,因而局部皮损治疗意义不大,应以全身治疗为主。
Objective: To analyze the clinicopathological features of metastatic carcinoma of the skin. Methods: The patient’s medical history and histological sections were analyzed. RESULTS: From 1975 to 1996, 36 cases of skin metastases accounted for 2.1% of the surgical cases in the same period, which occurred in the middle-aged and elderly patients. The ratio of males and females was 1:2.3; the position of metastases was determined by the location and spread of primary cancer. Methods: The clinical manifestations were nodularity in 32 cases (89%), inflammatory in 3 cases, and hard-skin-like in 1 case. The median survival time was 9 months in the whole group and 23 cases died within 6 months. CONCLUSIONS: The most common source of metastatic carcinoma of the skin is visceral cancer, which occurs most frequently in the advanced stage of cancer. Therefore, the treatment of local lesions is of little significance and should be based on systemic therapy.