以稀土固体超强酸SO2-4/TiO2/La3+为催化剂,氯乙酸与乙醇为原料合成氯乙酸乙酯。研究了氯乙酸与乙醇的摩尔比、催化剂用量、环己烷的用量、反应时间诸因素对产品收率的影响。结果表明:SO2-4/TiO2/La3+是合成氯乙酸乙酯的良好催化剂,适宜的反应条件如下:氯乙酸与乙醇的摩尔比为1∶3.0,催化剂的用量0.8g,环己烷用量15mL,反应2.0h,氯乙酸乙酯的收率可达92.7%。 Rare earth solid superacid SO2-4 / TiO2 / La3 + as catalyst, chloroacetic acid and ethanol as raw materials to synthesize ethyl chloroacetate. The effects of the molar ratio of chloroacetic acid to ethanol, the amount of catalyst, the amount of cyclohexane and the reaction time on the yield of the product were studied. The results showed that SO2-4 / TiO2 / La3 + was a good catalyst for the synthesis of ethyl chloroacetate. The suitable reaction conditions were as follows: the molar ratio of chloroacetic acid to ethanol was 1: 3.0, the amount of catalyst was 0.8g, the amount of cyclohexane was 15mL, The reaction 2.0h, the yield of ethyl chloroacetate up to 92.7%.