钒广泛用于各种重工业,但有关它的毒理资料较少,本文研究了硫酸氧钒对小鼠器官形成期的影响。用25～30 g瑞士种小鼠,适应性饲养10天后,以2∶1雌雄合笼,每天作雌鼠阴道涂片检查精子,以发现精子日为妊娠0天。将检出精子阳性雌鼠随机分成四组,每组22只,在妊娠第6～15天期间内,每天分别按37.5,75和150 mg/kg体重剂量灌饲硫酸氧钒(VOSO_4·5H_2O),对照组给予相应的蒸馏水。每天观察孕鼠毒性反应,记录孕鼠体重、食物消耗量和孕鼠死亡数。在妊娠第18天处死孕鼠,肉眼观 Vanadium is widely used in various heavy industries, but its toxicological data are few. This paper studies the effect of vanadyl sulfate on organ formation in mice. With 25 ~ 30 g Swiss species mice, adaptive feeding for 10 days, 2: 1 male and female cage, daily vaginal smear test female sperm to find sperm day is 0 days of pregnancy. Sperm-positive females were randomly divided into four groups (n = 22). During the 6th to 15th days of gestation, the female mice were fed with vanadyl sulfate (VOSO_4 · 5H_2O) at doses of 37.5, 75 and 150 mg / , The control group given the corresponding distilled water. Toxicity of pregnant rats was observed daily. The body weight, food consumption and the number of pregnant rats were recorded. Pregnant mice were sacrificed on the 18th day of gestation and the naked eye was observed