对于中晚期恶性肿瘤的治疗,除手术治疗外,目前最常用的是化疗及放疗。但是,由于放疗及化疗对肿瘤细胞缺乏选择性杀灭作用,且有不敏感的肿瘤细胞群体存在,通常疗效不佳。近几年来,由于对肿瘤具有明显选择性的单克隆抗体的出现,以及新型交联剂及交联方法的研制成功,肿瘤导向治疗的设想逐渐成为现实。这方面的研究正在世界范围内不断兴起,并深入发展,表现在如下几个方面: 研究面广:目前几乎所有先进国家都在进行此项研究工作。其中较出色者如英国Nott- For the treatment of advanced and advanced malignant tumors, except for surgical treatment, chemotherapy and radiotherapy are currently the most commonly used. However, due to the lack of selective killing of tumor cells by radiotherapy and chemotherapy, and the existence of insensitive tumor cell populations, the efficacy is usually poor. In recent years, the concept of tumor-directed therapy has gradually become a reality due to the emergence of monoclonal antibodies that are clearly selective for tumors, and the successful development of novel crosslinking agents and cross-linking methods. Research in this area is constantly rising in the world, and in-depth development in the following areas: Research is wide: At present, almost all advanced countries are carrying out this research work. Among the better ones such as Nott-British