例1,55岁,女性,鼻咽癌患者。取鼻咽部活检组织用直接法制备染色体标本。染色体分析发现,患者活检组织染色体众数为亚2倍体,并有染色体断片、断裂及裂隙等结构异常。同时还发现患者的1条2号染色体着丝粒区向外膨出,中空呈单叶螺旋浆状。例2,23岁,男性。取外周血按常规方法制备 Example 1, 55 years old, female, nasopharyngeal cancer patients. Take nasopharyngeal biopsy tissue prepared by direct method of chromosome specimens. Chromosome analysis revealed that the chromosome number of biopsies in patients was sub-diploid with structural abnormalities such as chromosome fragments, fractures and fissures. Also found in patients with a chromosome 2 centromere outward bulging hollow hollow single leaflet was. Example 2,23 years old, male. Peripheral blood taken by conventional methods