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观察了４６例肾移植患者血浆脂质代谢的改变，结果显示，肾移植患者血总胆固醇（ＴＣ）、甘油三酯（ＴＧ）、极低密度脂蛋白胆固醇（ＶＬＤＬ－Ｃ）和载脂蛋白（ａｐｏ）Ｂ１００明显升高，而ａｐｏＡＩ、ａｐｏＡⅡａｐｏＣⅡ／ａｐｏＣⅢ明显降低。同时还观察到，有心脑血管合并症的病者血ＴＣ、ＴＧ、ＴＣ／ＨＤＬ－ｃ、ａｐｏＢ１００升高ａｐｏＡＩ降低比合并症的病者更显著。上述结果表明，肾移植后脂质代谢有明显改变，且存在加速动脉硬化的倾向。
The changes of plasma lipid metabolism in 46 renal transplant recipients were observed. The results showed that the levels of total cholesterol (TC), triglyceride (TG), VLDL-C and apolipoprotein apo) B100 was significantly increased, while apoAI, apoA Ⅱ apoC Ⅱ / apoC Ⅲ decreased significantly. At the same time also observed that patients with cardiovascular and cerebrovascular complications TC, TG, TC / HDL-c, apoB100 increased apoAI decreased more significantly than the complication of patients. The above results show that there is a significant change in lipid metabolism after kidney transplantation, and there is a tendency to accelerate atherosclerosis.