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目的:观察莫沙必利联合氟西汀治疗功能性消化不良(FD)的临床疗效。方法:选择FD 94例,随机分为观察组与对照组各47例。观察组给予口服莫沙必利加氟西汀治疗;对照组口服莫沙必利加谷维素治疗。两组均加用奥美拉唑抑酸治疗。结果:两组均治疗4周后进行疗效评定,观察组总有效率85.1%,对照组53.2%,两组比较,差异非常显著(P<0.01)。结论:莫沙必利联合氟西汀治疗FD疗效较好。
Objective: To observe the clinical efficacy of mosapride and fluoxetine in the treatment of functional dyspepsia (FD). Methods: 94 cases of FD were selected and randomly divided into observation group and control group, 47 cases each. The observation group was given oral mosapride plus fluoxetine; the control group was given mosapride plus oryzanol. Both groups were treated with omeprazole acid suppression. Results: After 4 weeks treatment, the curative effect was evaluated in both groups. The total effective rate was 85.1% in the observation group and 53.2% in the control group. There was significant difference between the two groups (P <0.01). Conclusion: Mosapride combined with fluoxetine in the treatment of FD is better.