最近十几年来,在血吸虫病的研究中,由于运用了现代免疫学,特别是免疫病理学的有关知识,使我们对血吸虫病的发病学有了新的认识。大量的研究工作证明,免疫病理机制在血吸虫感染所致的各种疾病状态中起着关键的作用,即血吸虫病的许多组织损伤,并非是由血吸虫及其代谢产物本身对宿主组织的直接毒性作用引起,而是宿主对血吸虫抗原产生不同类型的变态反应的结果。因此有人认为血吸虫病本质上是一种免疫性疾病。目前,已经了解人感染血吸虫后发生的许多疾病现象,如尾蚴性皮炎、急性血吸虫病、肝脏慢性纤维阻塞损害和肾脏的损伤等,都和变态反应有关。本文着重介绍有关血吸虫卵肉芽肿形成的免疫病 In the past decade or so, in the study of schistosomiasis, we have gained a new understanding of the pathogenesis of schistosomiasis due to the use of the knowledge of modern immunology, especially immunopathology. Numerous studies have demonstrated that immunopathology plays a key role in various disease states caused by schistosomiasis, many of which are not caused by the direct toxic effects of schistosomes and their metabolites on host tissues But rather the host produces different types of allergic reactions to the schistosome antigen. So some people think that schistosomiasis is essentially an immune disease. At present, many diseases such as cercarial dermatitis, acute schistosomiasis, chronic liver fibrosis and renal damage have been known to have been associated with allergic reactions. This article focuses on immunological disease associated with schistosomal egg granuloma formation