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本文作者用~125I-UdR释放法检测了31例急性白血病患者、49名健康成人外周血NK活性,同时用微量CPE抑制法测定了其中27例患者和34名健康成人白细胞诱生干扰素水平。结果显示,急性白血病患者在不同病程阶段其IFN诱生能力和NK活性是有变化的;(1).化疗期与化疗间歇期无明显变化;(2)缓解期似比治疗前高,说明IFN水平和NK活性与病情转归有密切联系。当病情未缓解时,IFN水平和NK活性下降,而病
The authors tested the NK activity in peripheral blood of 31 patients with acute leukemia and 49 healthy adults with ~125I-UdR release assay and the leukocyte-induced interferon levels in 27 patients and 34 healthy adults by micro-CPE inhibition assay. The results showed that patients with acute leukemia at different stages of its induction of IFN activity and NK activity is a change; (1) the chemotherapy period and no significant changes during the intermittent chemotherapy; (2) remission seems higher than before treatment, indicating IFN Level and NK activity and prognosis are closely linked. When the disease is not alleviated, IFN levels and NK activity decreased, and the disease