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用图像分析仪测定33例儿童石蜡包埋组织的AgNORs参数（数量和面积），探讨AgNORs参数与儿童NHL生存期的关系及临床工作分类与AgNORs参数的关系。结果显示：1）生存与AgNORs参数显著相关。生存＜1年和＞1年，AgNORs参数差异极显著（P＜0．01）。AgNORs数量多、面积大，生存时间短，反之亦然。2）年龄、工作分类与AgNORs显著相关。小、中年龄段组及低度恶性组的AgNORs均值数小，大年龄段组及高度恶性组的AgNORs均值数大。3）年龄、工作分类与生存显著相关。小、中年龄段组1年生存率明显好于大年龄段组；低度恶性组1年生存率明显好于高度恶性组。AgNORs可作为判断儿童NHL预后的一个新指标。
AgNORs parameters (number and area) of paraffin-embedded tissues of 33 children were measured by image analyzer. The relationship between AgNORs parameters and survival of children with NHL and the relationship between clinical classification and AgNORs parameters were analyzed. The results showed that: 1) survival was significantly correlated with AgNORs parameters. Differences in AgNORs parameters were significant (P <0.01) for survival <1 year and> 1 year. AgNORs number, area, survival time is short, and vice versa. 2) age, job classification and AgNORs significantly related. The mean AgNORs for small, middle-age and low-grade groups were small, and mean AgNORs for large-age groups and highly-malignant groups were large. 3) Age, job classification and survival were significantly correlated. The 1-year survival rate of the small and middle-aged group was significantly better than that of the large-age group. The 1-year survival rate of the low-grade group was significantly better than that of the high-grade group. AgNORs can be used as a new indicator of prognosis in children with NHL.