纯钛种植体部分暴露于口腔中,在种植体植入、愈合和行使功能的各环节中,种植体周组织均存在着被细菌感染的危险。细菌附着在种植体上会影响新生骨的生长,导致支持骨的丧失,从而降低骨-种植体界面的机械稳定性,这是种植体失败的主要原因之一。因此控制种植体表面细菌聚集和粘附,对于预防和治疗种植体周感染具有重要意义。本文就纯钛种植体表面抗菌改性的研究进展作一综述。 Titanium implants are partially exposed to the oral cavity and there is a risk of bacterial infection in the peri-implant tissue in all aspects of implantation, healing, and exercise of the implant. Bacterial attachment to the implant affects the growth of new bone, resulting in loss of support for the bone, thereby reducing the mechanical stability of the bone-implant interface, which is one of the major causes of implant failure. Therefore, the control of implant surface bacteria accumulation and adhesion, for the prevention and treatment of implant infection is of great significance. This review summarizes the research progress of antimicrobial modification of pure titanium implants.