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本文介绍了一种分析致癌物-DNA加合物的新方法——“磷后标记方法及其改良过程,并阐述了该法在检测分析致癌物-DNA加合物的形成及结构、持续时间等方面的应用以及人类DNA加合物的研究现状。该方法的不断改进及应用无疑为人类接触致癌物的早期生物学监测及危险性评价提供了一个强有力的工具。
This article describes a new method for the analysis of carcinogen-DNA adducts - the "post-phosphorus labeling method and its improvement, and describes the method for the detection and analysis of carcinogen-DNA adduct formation and structure, duration Etc. The continuous improvement and application of this method will undoubtedly provide a powerful tool for the early biological monitoring and risk assessment of human exposure to carcinogens.