急性胰腺炎(Acute pancreatitis,AP)是临床常见的急腹症之一,其发病机制较为复杂,炎性细胞因子、趋化因子、黏附分子等多种因子参与并起着非常重要的作用[1],而近年来的大量研究发现,核因子-κB(nuc lear factor kappa B,NF-κB)在AP的发生及转归中起着重要作用[2-3]。NF-κB是 Acute pancreatitis (AP) is one of the common clinical acute abdomen diseases. The pathogenesis of AP is complicated. Many factors such as inflammatory cytokines, chemokines and adhesion molecules play a very important role [1 In recent years, a large number of studies have found that nuclear factor-kappa B (NF-κB) play an important role in the occurrence and prognosis of AP [2-3]. NF-κB is