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本文报道吲哚美辛对梗阻性黄疸血流动力学的调节作用。将梗阻性黄疸分为非吲哚美辛组(A组)、吲哚美辛术前组(B组)、吲哚美辛术后组(C组)。并与单纯胆囊结石(D组)比较。结果表明梗阻性黄疸各组SV、CO和CI显著高于D组(P<0.01),MAP、SVR和PVBF显著低于D组(P<0.01)。B、C组MAP、SVR和PVBF显著高于A组(P<0.01),但与D组比较仍有极显著差异(P<0.01)。因此,作者认为吲哚美辛有改善循环功能、PVBF和肝功能作用,解除胆道梗阻后上述指标进一步改善。
This article reports the regulation of indomethacin on the hemodynamics of obstructive jaundice. Obstructive jaundice was divided into non-indomethacin group (group A), indomethacin preoperative group (group B) and indomethacin postoperative group (group C). And compared with simple gallstones (group D). The results showed that SV, CO and CI in obstructive jaundice groups were significantly higher than those in group D (P <0.01), MAP, SVR and PVBF were significantly lower than those in group D (P <0.01). The MAP, SVR and PVBF in group B and C were significantly higher than those in group A (P <0.01), but there was still significant difference compared with group D (P <0.01). Therefore, the authors believe that indomethacin can improve circulatory function, PVBF and liver function, to relieve the biliary obstruction after the above indicators to further improve.