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目的评价流变溶栓序贯治疗门脉系静脉血栓形成的临床疗效。方法11例门脉系静脉血栓形成病例经流变溶栓序贯治疗,包括血管腔内成形术、内支架植入术进行门静脉开通治疗,观察门静脉再通、临床症状缓解和并发症发生情况。结果10例开通成功,开通率90.9%。整个流变溶栓过程所需时间<30 m in,5例溶栓后对基础狭窄行经皮血管腔内成形术,2例行内支架治疗,无并发症发生,随访5~14个月,均生存无复发。结论流变溶栓治疗门静脉系血栓形成具有损伤小、溶栓能力强的特点;结合序贯治疗方案,则更加合理,治疗效果更明确、持久。
Objective To evaluate the clinical effect of sequential thrombolytic therapy on portal venous thrombosis. Methods Eleven patients with portal venous thrombosis were treated with sequential thrombolytic therapy, including endovascular angioplasty and endovascular stent implantation. Portal vein recanalization, clinical symptom relief and complications were observed. Results 10 cases opened successfully, the opening rate of 90.9%. The total time required for rheological thrombolysis was less than 30 mins. Five patients underwent basic thrombolysis with percutaneous transluminal angioplasty after thrombolysis and two patients received endovascular stent placement. No complications occurred and were followed up for 5 to 14 months No recurrence of survival. Conclusion The thrombolytic therapy for thrombosis of portal vein has the characteristics of small damage and strong thrombolytic ability. Combined with sequential treatment, it is more reasonable and the treatment effect is more definite and lasting.