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目的 :评价佳贝和欧可芬滴眼液在白内障术中维持瞳孔散大及术后抗炎作用疗效。方法 :随机分组 (佳贝组、欧可芬组和对照组 )研究 86名白内障患者术前应用两种药物后 ,白内障术中瞳孔大小的改变以及对卡米可林(氨甲酰胆碱 ,Carbacol)缩瞳作用的影响 ;以地塞米松滴眼液为对照 ,研究应用两种滴眼液对术后角膜后KP和房水混浊度的影响 ,以及对术眼眼压的影响。结果 :与对照组相比 ,佳贝和欧可芬都能有效抑制术中的瞳孔缩小 (P <0 .0 0 1 ) ,且不影响卡米可林的缩瞳作用 ;两者都能有效降低术眼术后前房炎症反应 ,抗炎效果与地塞米松相似 ,且不引起早期眼压的改变 (P >0 .0 5)。结论 :佳贝和欧可芬能安全、有效地维持白内障术中瞳孔大小 ,降低术后炎症反应。
OBJECTIVE: To evaluate the efficacy of charcoal and opulent eyedrops for maintaining mydriasis and postoperative anti-inflammatory effects in cataract surgery. Methods: Eighty-six cataract patients were randomly divided into groups (beibei group, oprofen group and control group) to study the changes of pupil size in cataract surgery and the effects of carpacol (carbapenem) The effect of two kinds of eye drops on postoperative corneal posterior corneal KP and aqueous humor turbidity was studied. The effect of dexamethasone eye drops on intraocular pressure was also studied. Results: Compared with the control group, both bevacizumab and oxycodone were able to effectively inhibit the intraoperative miosis (P <0.01), and did not affect the miotic effect of camicolin; both were effective Anterior chamber inflammation after surgery, anti-inflammatory effect and dexamethasone similar, and did not cause changes in early intraocular pressure (P> 0.05). Conclusion: Gabe and Octocortin can safely and effectively maintain the pupil size in cataract surgery and reduce the postoperative inflammatory response.