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新生儿由于胃肠道发育不成熟或疾病影响均可造成喂养不耐受,其胃肠动力的发育与胃肠的消化、吸收功能发育相比相对迟缓, 故喂养不耐受在新生儿尤其是早产儿和危重症新生儿中很常见。喂养不耐受影响机体内环境的稳定及生长发育,肠道喂养的进展缓慢通常导致肠外营养的延长,而这将使新生儿易患坏死性小肠结肠炎(NEC)、肝功能障碍并使住院时间延长。近年来发现红霉素对胃肠道有促动力作用,国内外学者对其进行了一系列的研究,力求探索出关于喂养不耐受诊断及治疗的适当策略。
Neonates due to gastrointestinal tract immaturity or disease can cause feeding intolerance, the development of gastrointestinal motility and gastrointestinal digestion, the development of relatively slow absorption function, so feeding intolerance in neonates, especially Very common in preterm and critically ill neonates. Feeding intolerance affects the stability and growth of the environment in the body and slow progress in bowel feeding usually leads to prolonged parenteral nutrition that will predispose the newborn to necrotizing enterocolitis (NEC), liver dysfunction and Hospitalization extended. In recent years, erythromycin has been found to have an impetus effect on the gastrointestinal tract. Scholars at home and abroad have carried out a series of researches on it and are trying to find appropriate strategies for the diagnosis and treatment of feeding intolerance.