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肺炎衣原体(Cpn)感染可能参与动脉粥样硬化(AS)的发生发展,但针对肺炎衣原体的抗生素治疗在冠心病的二级预防中是否有效仍是一个悬而未决的问题。目前的研究表明,Cpn可能是AS的启动因素,但并不参与其发生、发展。大规模临床试验并没有得出抗衣原体治疗使冠心病患者获益的结论。
Chlamydia pneumoniae (Cpn) infection may be involved in the development of atherosclerosis (AS). However, whether antibiotic treatment of Chlamydia pneumoniae is effective in the secondary prevention of coronary heart disease remains a pending issue. The current study shows that Cpn may be the initiating factor of AS, but it does not participate in its occurrence and development. Large-scale clinical trials did not conclude that anti-Chlamydia treatment benefit patients with coronary heart disease.