论文部分内容阅读
目的分析卡培他滨联合奥沙利铂治疗进展期老年胃癌的临床疗效。方法 90例进展期老年胃癌患者,根据治疗时所采用方案不同分为对照组(40例)和研究组(50例)。对照组行替吉奥联合奥沙利铂治疗,研究组行卡培他滨联合奥沙利铂治疗,对资料进行对比和分析。结果研究组生活质量评分(QOL)为(50.34±3.17)分,显著高于对照组的(43.51±2.87)分(P<0.05);研究组总有效率为46.00%,显著高于对照组的15.00%,差异具有统计学意义(P<0.05)。结论卡培他滨联合奥沙利铂治疗进展期老年胃癌的临床疗效显著,值得临床推广。
Objective To analyze the clinical efficacy of capecitabine combined with oxaliplatin in the treatment of advanced gastric cancer. Methods Ninety elderly patients with advanced gastric cancer were divided into control group (n = 40) and study group (n = 50) according to the different regimens adopted during treatment. The control group was treated with oxaliplatin instead of GIO, and the study group received capecitabine combined with oxaliplatin. The data were compared and analyzed. Results The QOL of the study group was (50.34 ± 3.17) points, which was significantly higher than that of the control group (43.51 ± 2.87) (P0.05). The total effective rate was 46.00% in the study group, which was significantly higher than that of the control group 15.00%, the difference was statistically significant (P <0.05). Conclusion Capecitabine combined with oxaliplatin in the treatment of advanced gastric cancer has significant clinical efficacy and is worthy of clinical promotion.