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选取我院2012年1月~2014年12月收治的73例肝硬化合并上消化道出血患者。分为试验组37例和对照组36例。两组患者均给予奥曲肽,试验组患者在此基础上给予凝血酶,比较两组患者的止血效果、止血时间、住院时间和48h再出血率。结果试验组治疗效果为94.60%,对照组为72.22%,组间差异有统计学意义(P<0.05);试验组患者止血时间、住院时间和48h再出血率均显著优于对照组,组间差异有统计学意义(P<0.05)。临床上对肝硬化合并上消化道出血患者在奥曲肽治疗的基础上加用凝血酶,缩短了止血时间和住院时间,降低了再出血率,治疗效果显著增加。
Selected from January 2012 to December 2014 in our hospital admitted 73 cases of patients with cirrhosis and upper gastrointestinal bleeding. Divided into experimental group 37 cases and control group 36 cases. Both groups were given octreotide. Patients in the test group were given thrombin on this basis. The hemostatic effect, bleeding time, length of hospital stay and rate of rebleeding at 48 hours were compared between the two groups. Results The therapeutic effect was 94.60% in the trial group and 72.22% in the control group, with significant difference between the two groups (P <0.05). The bleeding time, hospitalization time and rebleeding rate at 48h in the experimental group were significantly better than those in the control group, The difference was statistically significant (P <0.05). Clinically, patients with cirrhosis and upper gastrointestinal bleeding are treated with octreotide plus thrombin to shorten the bleeding time and hospital stay, reduce the rate of rebleeding, the treatment effect was significantly increased.