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目的通过比较高原红细胞增多症(HAPC)患者与正常对照组肺通气功能和弥散功能的变化,探讨高红症肺功能受损的原因及危险因素。方法测定30例高红症患者与正常对照组的肺功能,并就肺通气和弥散功能方面进行比较。结果高红组患者肺功能各项通气指标(VCMAX、FVC、FEV1、FEV1%FVC、PEF、FEF25、FEF50、FEF75、MMEF75/25)及弥散指标(TLCO/VA)均降低。结论高红症患者有明显的肺功能损害,主要表现为肺泡通气量明显降低和(或)弥散功能降低。
Objective To investigate the causes and risk factors of pulmonary function impairment in hyperchromemen by comparing the changes of pulmonary ventilation and diffusing function in patients with high altitude polycythemia (HAPC) and normal controls. Methods The lung function of 30 hyperlipidemia patients and normal control group were measured and compared in terms of pulmonary ventilation and diffuse function. Results The indexes of pulmonary function (VCMAX, FVC, FEV1, FEV1% FVC, PEF, FEF25, FEF50, FEF75 and MMEF75 / 25) and the indexes of diffusion (TLCO / VA) were all decreased in high red group. Conclusions The patients with hyperkinetic disease have obvious pulmonary dysfunction. The main manifestations are decreased alveolar ventilation volume and / or decreased diffusion function.