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目的探讨手术中种植放射性碘125微粒近距离内照射治疗食管癌的疗效。方法采取前瞻性对照研究的方法研究手术中种植放射性碘125微粒近距离内照射治疗食管癌的疗效,将患者随机分为内照射组和单纯手术组,内照射组采用食管癌根治+碘125微粒植入,单纯手术组仅采用食管癌根治术。比较二组术后1~5 a生存率。结果二组患者术后1~5 a生存率差异有统计学意义(P<0.05)。结论手术中种植放射性碘125微粒近距离内照射治疗食管癌术后生存率明显改善,为食管癌治疗开辟了新的途径。
Objective To investigate the efficacy of intracranial radioactive iodine 125 microinjection in the treatment of esophageal cancer. Methods A prospective controlled study was conducted to evaluate the efficacy of intracavitary 125-radioluded brachytherapy in the treatment of esophageal cancer. The patients were randomly divided into internal radiotherapy group and operation alone group. The internal radiotherapy group was treated with radiotherapy of 125 I-125 Implantation, surgery alone group only with esophageal cancer radical mastectomy. The survival rates of the two groups after 1 ~ 5 days were compared. Results There was significant difference in survival rate between 1 and 5 years after operation in both groups (P <0.05). Conclusion Surgical treatment of radioactive iodine 125 microparticle brachytherapy for esophageal cancer after surgery significantly improved the survival rate, which opened up a new way for the treatment of esophageal cancer.