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冠状动脉疾病常常是由于冠状动脉壁脂肪沉积使得动脉硬化而引起。动脉壁的脂肪沉积引起了周围纤维组织生成从而形成斑块使管腔狭窄而阻塞血流。如果有50%以上的血流受阻就会危及生命。冠状动脉疾病在加拿大是一个主要的死亡原因。这是饮食、生活方式、遗传和医学诸因素复杂的相互影响的结果。已证实的若干危险因素包括吸烟、嗜酒、高血压、遗传缺陷(低d-脂蛋白血症)、高脂血症、碳水化合物和脂肪摄入过多、年龄、性别、种族、糖尿病、肥胖、以及使用类固醇和β-肾上腺素能阻滞药物等。
Coronary artery disease is often caused by atherosclerosis due to coronary artery wall fat deposits. The deposition of fat on the arterial wall causes the formation of surrounding fibrous tissue that forms plaque that narrows the lumen and blocks the blood flow. If more than 50% of the blood flow is blocked will be life-threatening. Coronary artery disease is a leading cause of death in Canada. This is the result of the complex interplay of factors such as diet, lifestyle, genetics and medicine. Several risk factors have been proven to include smoking, alcohol abuse, high blood pressure, genetic defects (low d-lipoproteinemia), hyperlipidemia, excessive carbohydrate and fat intake, age, gender, race, diabetes, obesity , And the use of steroids and β-adrenergic block drugs.