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目的了解海岛地区孕产妇梅毒发病情况及对围产儿结局的影响,为该地区孕产妇梅毒防治决策提供依据。方法回顾性分析2008-2009年度在舟山市妇幼保健院住院分娩的梅毒感染孕产妇其妊娠结局及新生儿的转归情况。结果 51例妊娠期梅毒患者中,孕前及孕早、中孕期确诊并正规治疗组早产、死胎、死产的发生率、先天梅毒儿的发生率明显低于孕晚期确诊未正规治疗组。结论通过对产前筛查出妊娠期梅毒后,及早、足量、正规的抗梅毒治疗能有效地降低流产、早产、死产和分娩先天梅毒儿的发生率。对妊娠早、中期发现的梅毒患者不必终止妊娠,通过正规、足量的抗梅毒治疗可以避免不良妊娠结局的发生。尽可能加强宣教,提高孕妇系管率,孕期及早进行梅毒筛查,发现异常及时给予正规、足量治疗。
Objective To understand the incidence of syphilis among pregnant women in island area and its effect on the outcomes of perinatal infants, and to provide basis for the prevention and control of syphilis among pregnant women in the area. Methods A retrospective analysis of 2008-2009 in Zhoushan City, MCH hospital delivery of syphilis infection in pregnant women pregnant women outcome outcomes and outcome. Results The incidence of preterm birth, stillbirth and stillbirth in congenital syphilis and gestational syphilis in 51 gestational months and before pregnancy and in the second trimester was significantly lower than that in the third trimester of pregnancy. Conclusion Through the prenatal screening for gestational syphilis, early, adequate and regular anti-syphilis treatment can effectively reduce the incidence of abortion, premature birth, stillbirth and childbirth congenital syphilis. Pregnancy, early detection of syphilis in mid-term patients do not have to terminate the pregnancy, through regular, adequate anti-syphilis treatment can prevent the occurrence of adverse pregnancy outcomes. As far as possible to strengthen the mission, to increase the rate of pregnant women, syphilis screening early pregnancy and found abnormal timely and adequate, adequate treatment.