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目的了解实施药学干预措施前后Ⅰ类切口围手术期抗菌药物使用情况及药学干预效果。方法抽取解放军413医院2013年1月至2016年12月Ⅰ类切口手术病历6205份进行统计分析,其中药学干预前2675份,药学干预后3530份。结果药学干预前Ⅰ类切口围手术期抗菌药物的使用率为82.43%,药学干预后下降至41.02%,干预后在给药时机、药物选择、给药疗程方面有较大的提高。结论药学干预后某院Ⅰ类切口围手术期预防性使用抗菌药物仍存在不合理现象,需进一步加大管理力度,提高抗菌药物的合理应用。
Objective To understand the perioperative use of antimicrobial agents and the effect of pharmaceutical interventions before and after the implementation of pharmaceutical interventions. Methods A total of 6205 cases of type Ⅰ incision surgeries were collected from the 413 Hospital of People’s Liberation Army from January 2013 to December 2016, of which 2675 were before the pharmacy intervention and 3530 after the pharmaceutical intervention. Results Before the intervention, the usage rate of perioperative antimicrobials in class Ⅰ incision was 82.43%, and dropped to 41.02% after the intervention. The intervention time, drug selection and medication course were greatly improved. Conclusion There is still an irrational use of antimicrobial agents for perioperative prevention of Class I incision in a hospital after pharmacy intervention. Management efforts need to be further intensified to improve the rational use of antimicrobial agents.