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目的 :探讨支原体肺炎患儿机体免疫功能状况和特点。方法 :采用流式细胞仪和激光免疫比浊法检测 3 7例支原体肺炎患儿血清T细胞亚群和免疫球蛋白水平 ,并与正常对照组相比较。结果 :(1)患儿组血清CD3、CD4、CD4 CD8水平与正常对照组相比明显下降 ,差异显著 (P <0 0 5 ) ;而CD8水平无明显变化 (P >0 0 5 )。 (2 )患儿血清免疫球蛋白水平与正常对照组相比无明显差异 (P >0 0 5 )。结论 :支原体肺炎患儿以细胞免疫功能降低为主 ,体液免疫不占主导地位
Objective: To investigate the status and characteristics of immune function in children with Mycoplasma pneumonia. Methods: Serum T cell subsets and immunoglobulin levels in 37 children with mycoplasma pneumonia were detected by flow cytometry and laser immunoturbidimetry, and compared with the normal control group. Results: (1) Serum levels of CD3, CD4 and CD4 CD8 in children were significantly lower than those in normal controls (P <0.05), but no significant changes in CD8 levels (P> 0.05). (2) Serum immunoglobulin levels in children with no significant difference compared with the normal control group (P> 0.05). Conclusion: Mycoplasma pneumonia in children with reduced cellular immunity, humoral immunity does not dominate