新生儿围生期窒息是引起新生儿缺氧缺血性脑病 (ＨＩＥ)的最主要原因 ,窒息可引起多器官功能损害 ,重度窒息是导致新生儿致死致残的主要原因之一。近年来 ,血清ＬＤＨ、ＡＳＴ、ＣＫ及其同工酶活性的增高可以作为多器官损害程度的评价指标多有报道 ,窒息后新生儿ＨＢＤＨ、ＨＢ Perinatal asphyxia neonatorum is caused by neonatal hypoxic-ischemic encephalopathy (HIE) the most important reason, asphyxia can cause multiple organ dysfunction, severe asphyxia is one of the main causes of neonatal death caused by disability. In recent years, serum LDH, AST, CK and its isoenzyme activity increased as a multi-organ damage degree evaluation index are more reported, neonatal asphyxia neonatal HBDH, HB