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目的分析复发上皮性卵巢癌,采用洛铂联合多西他赛治疗的临床效果。方法 35例复发转移性卵巢癌患者,均采用洛铂联合多西他赛治疗,分析其治疗效果。结果 35例患者临床症状均明显改善,腹腔积液消失,近期疗效总有效率为48.6%,疾病控制率为80%,2年死亡率65.7%。33例患者出现骨髓抑制,6例患者出现恶心呕吐。结论洛铂联合多西他赛治疗复发转移性卵巢癌具有较高的治疗效果,近期疗效高,无明显毒副反应,值得临床推广使用。
Objective To analyze the clinical effect of lobaplatin combined with docetaxel in the treatment of recurrent epithelial ovarian cancer. Methods 35 patients with recurrent metastatic ovarian cancer were treated with lobaplatin and docetaxel, and the therapeutic effect was analyzed. Results The clinical symptoms of all the 35 patients were significantly improved. The effusion disappeared. The total effective rate was 48.6%, the disease control rate was 80%, and the 2-year mortality rate was 65.7%. Thirty-three patients had myelosuppression and 6 patients had nausea and vomiting. Conclusion Losoplatin combined with docetaxel in the treatment of recurrent metastatic ovarian cancer has a high therapeutic effect, the recent curative effect is high, no obvious side effects, worthy of clinical promotion and use.