论文部分内容阅读
目的了解冠状动脉病变患者血尿酸水平(UA)与血脂的变化及临床意义。方法 68例经冠状动脉造影(CAG)证实至少有1支以上冠脉主要分支病变狭窄≥50%作为观察组,45例CAG正常者为对照组,分别检测UA、血脂谱水平,进行统计学处理。结果观察组UA、TC、TG、LDL-C均高于对照组,HDL-C低于对照组,差异有统计学意义(p<0.05),随着冠脉病变支数的增加,UA也增加,观察组内三支病变及双支病变患者UA与单支病变者比较差异均有统计学意义(p<0.05)。结论 UA与冠状动脉病变程度呈正相关,UA、TC、TG、LDL-C水平增高以及HDL-C降低是冠脉病变程度的重要危险因素。
Objective To investigate the changes and clinical significance of serum uric acid (UA) and serum lipids in patients with coronary artery disease. Methods 68 cases of coronary artery angiography (CAG) confirmed at least one branch of coronary artery stenosis ≥ 50% as observation group, 45 cases of normal CAG as control group, respectively, UA, lipid profile were measured for statistical analysis . Results The levels of UA, TC, TG and LDL-C in the observation group were higher than those in the control group, and the HDL-C levels were lower than those in the control group (p <0.05). UA also increased with the number of coronary lesions . There were significant differences between UA and single vessel lesions in the three lesions and double vessel lesions in the observation group (p <0.05). Conclusions UA is positively correlated with the severity of coronary artery disease. The increase of UA, TC, TG and LDL-C and the decrease of HDL-C are important risk factors of coronary artery disease.