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目的：研制一种以卡波母974为基质、含有甲硝唑及盐酸林可霉素的缓释凝胶，并制定质量控制标准。方法：采用分光光度法分别对上述两种药物进行含量测定。结果与结论：甲硝唑平均回收率为99．27％、RSD为1．15％；盐酸林可霉素平均回收率为100．17％，RSD为2．22％。
OBJECTIVE: To develop a sustained-release gel containing metronidazole and lincomycin hydrochloride based on Kaposi 974 as matrix, and to develop a quality control standard. Methods: The contents of these two drugs were determined by spectrophotometry. RESULTS AND CONCLUSION: The average recovery of metronidazole was 99.27% and the RSD was 1.15%. The average recovery of lincomycin hydrochloride was 100.17% with RSD of 2.22%.