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系统性红斑狼疮(简称SLE)是一种自身免疫性疾病。对SLE患者进行免疫状态测定,有助于该病的诊断和治疗,并能进一步了解其发病机理。本文就30例SLE患者部分免疫反应测定的结果作初步报告。受检对象和方法一、对象,系1976年8月至1977年12月在省人民医院及省立医院就诊的30例SLE患者。诊断参照美国风湿病协会提出的标准,即有典型的皮肤损害、全身症状和实验室检查异常(包括周围血中找到LE细胞及/或血清抗核抗体阳性)。本组男2例,女28例,年龄15~58岁,平均34岁。多数患者接受强的松治疗(5~40毫克/日),部分病例合并应用细胞毒药物,其中10例单独或并用左旋咪唑(LMS)治疗(45~135毫克/日),间歇或连续用药。
SLE is an autoimmune disease. SLE patients with immune status determination, contribute to the diagnosis and treatment of the disease, and to further understand its pathogenesis. In this paper, 30 cases of SLE patients with partial immune response results for the initial report. Subjects and methods subject, object, from August 1976 to December 1977 in the Provincial People’s Hospital and Provincial Hospital, 30 cases of SLE patients. The diagnosis was based on the criteria set by the American College of Rheumatology with typical skin lesions, systemic symptoms and laboratory abnormalities (including LE cells found in the peripheral blood and / or serum anti-nuclear antibody positive). The group of 2 males and 28 females, aged 15 to 58 years, mean 34 years. Most patients received prednisone (5-40 mg / day) and in some cases combined with cytotoxic drugs, 10 of them were treated alone or in combination with LMS (45- 135 mg / day), either intermittently or continuously.