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作者报告了一组骨髓增生不良性急性白血病(AL)患者的临床特征,对治疗的反应以及用强烈的治疗缓解率高和存活期长。 29例患者,男:女=3:1,年龄15~79岁,有25例年龄≥50岁。均经骨髓活检证实是骨髓细胞过少性AL,因治疗引起的白血病除外。其中20例是重度或中度骨髓增生不良(造血组织分别<15%及占15~30%),9例是轻度骨髓增生不良(造血组织占30~40
The authors report the clinical characteristics of a group of patients with myelodysplastic-acute leukemia (AL), their response to therapy, and their high rate of remission and intensive survival with intensive treatment. 29 patients, male: female = 3: 1, aged 15 to 79 years, 25 patients ≥50 years of age. Bone marrow biopsy confirmed that bone marrow cells are too few AL, except for treatment-induced leukemia. Twenty of them were patients with severe or moderate myelodysplasia (15% in hematopoietic tissues and 15 to 30% in patients), and 9 were mild myelodysplasia (30 to 40 in hematopoietic tissue