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本文内容有助于外科医师正确理解口服避孕药对外科临床的影响.避孕失败口服避孕药的妇女应用其它药物时所产生的相互作用可使避孕失败.Reimers等对此首先发表的临床报告指出,口服避孕药与利福平或其它抗结核药物併用时可出现异常出血.减弱或消除避孕效果的多数药物的相互作用具有某些诱导微粒体酶的作用,如抗生素和抗惊厥药.利福平和灰黄霉素可分别阻碍和减弱口服避孕药的作用.四环素与口服避孕药的相互作用尚未明确.当这类药物与口服避孕药併用时,应劝告病人采用屏障法(barrier method)避孕.
This article helps surgeons correctly understand the clinical impact of oral contraceptives clinical contraceptive failure contraceptive oral contraceptive use of other drugs when the interaction can make contraception failure.Reimers et al first published clinical reports that, Oral contraceptives may be associated with abnormal bleeding when used in combination with rifampicin or other anti-TB drugs Most drug interactions that attenuate or eliminate contraceptive effects have the effect of inducing microsomal enzymes, such as antibiotics and anticonvulsants. Griseofulvin, respectively, hinder and weaken the role of oral contraceptives.The interaction of tetracycline and oral contraceptives is not yet clear.When such drugs and oral contraceptives and should be advised to use the barrier method (barrier method) contraception.