骨髓基质的脂细胞不同于髓外的脂细胞;骨髓脂细胞集落的产生已证明与造血再生有密切关系。而骨髓微环境缺陷已知是AA主要原因之一。为此,作者观察了AA病人骨髓脂细胞集落形成能力(Adipo-CFC),CFU F和骨髓基质细胞产生的集落刺激活性(CSA),并与骨髓异常增生综合征(MDS),IDA和正常人进行比较。CFU-F和Adipo-CFC的试验方法按Hirata J等(1986)法完成。培养14天,弃培养液,瓶底风干,用Giemsa和油红O染色,>50个细胞为一个CFC-F,>20个脂细胞为一个adipo-CFC。结果表明,IDA病人治疗前Adipo-CFC高于AA Bone marrow stromal adipocytes differ from extramedullary adipocytes; the production of myeloid adipose myeloid colonies has been shown to be closely linked to hematopoietic regeneration. The bone marrow micro-environmental defects are known to be one of the major causes of AA. To this end, we examined Adipo-CFC, CFU F, and colony-stimulating activity (CSA) produced by bone marrow stromal cells in AA patients and compared with those in patients with myelodysplastic syndrome (MDS), IDA, and normal individuals Compare. The test methods for CFU-F and Adipo-CFC were performed according to Hirata J et al. (1986). After 14 days of culture, the medium was discarded, the bottom of the flask was air-dried, stained with Giemsa and Oil Red O,> 50 cells were one CFC-F, and> 20 adipocytes were one adipo-CFC. The results showed that IDA patients before treatment Adipo-CFC higher than AA