男4例,女1例,发病年龄16～35岁,平均26岁。3例与患手足口病的子女有接触史,1例与同学手足口病患者有接触史,1例接触史不详。5例发病均无明显前驱症状,1例患儿有畏寒、发热、乏力、食欲不振等前驱症状。成人从接触患儿至发病时间约1～7天。表现为口腔皮疹3例;手指、掌跖皮疹5例; 4 males and 1 females, the age of onset of 16 to 35 years, mean 26 years. 3 cases had contact history with children with HFMD, 1 case had contact history with HFMD students, and 1 case had no history of exposure. There was no obvious prodromal symptom in 5 cases. One case had the prodromal symptoms of chills, fever, fatigue, loss of appetite. Adult contact with children from onset to about 1 to 7 days. Manifested as oral rash in 3 cases; finger, palmar plantar rash in 5 cases;