论文部分内容阅读
目的:分析河北省2010~2012年儿童恶性肿瘤发病死亡情况以及1974~2012年儿童恶性肿瘤死亡趋势。方法:收集河北省肿瘤登记地区2010~2012年肿瘤登记资料,估计河北省0~14岁儿童恶性肿瘤发病和死亡情况,并与三次死因回顾调查资料进行比较,分析河北省儿童恶性肿瘤死亡趋势。采用1982年中国标化人口构成和Segi’s世界人口构成分别计算中国和世界人口年龄标化发病/死亡率。结果:2010~2012年河北省肿瘤登记地区儿童恶性肿瘤发病率和世界标化率分别为7.85/10万和7.73/10万。男性发病率和世标率分别为8.53/10万和8.38/10万,女性发病率和世标率分别为7.07/10万和6.97/10万,男性高于女性。河北省儿童恶性肿瘤发病第一位的是白血病,其次为脑及中枢神经系统肿瘤、恶性淋巴瘤、肝癌和结直肠癌。1973~1975年,1990~1992年,2004~2005年和2010~2012年四个时期河北省儿童恶性肿瘤世界标化死亡率分别为5.31/10万,3.11/10万,4.47/10万和4.24/10万,呈小幅波动,整体呈下降趋势。结论:河北省儿童恶性肿瘤疾病负担较重,应提高对儿童恶性肿瘤的预防和早诊早治。
Objective: To analyze the incidence of malignant tumor in children from 2010 to 2012 in Hebei province and the death rate of malignant tumors in children from 1974 to 2012. Methods: Tumor registration data from 2010 to 2012 in Hebei province were collected to estimate the incidence and mortality of malignant tumors in children aged 0 ~ 14 years in Hebei Province. The data were compared with the retrospective data of three death causes to analyze the death trend of children with malignant tumor in Hebei province. The age-standardized morbidity / mortality of China and the world’s population were calculated respectively using the composition of China’s standardized population in 1982 and Segi’s world population. Results: The incidence of malignant tumors and the world standardization rate of children with tumor registration in Hebei Province from 2010 to 2012 were 7.85 / 100000 and 7.73 / 100000 respectively. The prevalence rate of the male and the world standard rate were 8.53 / 100000 and 8.38 / 100000 respectively. The incidence rate of the female and the world standard rate were 7.07 / 100,000 and 6.97 / 100,000, respectively, higher in males than in females. Hebei Province, the first incidence of children with malignant leukemia, followed by brain and central nervous system tumors, malignant lymphoma, liver cancer and colorectal cancer. The standardized mortality rates of childhood malignancies in Hebei province from 1973 to 1975, from 1990 to 1992, from 2004 to 2005 and from 2010 to 2012 were 5.31 / 100000, 3.11 / 100000, 4.47 / 100000 and 4.24 / 100,000, showing a slight fluctuation, the overall downward trend. Conclusion: The burden of disease of children with malignant tumor in Hebei Province is heavier. Prevention, early diagnosis and early diagnosis and treatment of children with malignant tumor should be improved.