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目的研究分析急性脊髓炎的临床特征及激素治疗的疗效。方法对47例急性脊髓炎患者的临床资料进行回顾性分析,总结急性脊髓炎的临床特征。根据用药不同将患者分为治疗组(23例)和对照组(24例)。治疗组患者给予甲基强的松龙治疗,对照组患者采用地塞米松治疗,分析两组患者的临床治疗效果。结果发病前患者普遍存在感染情况,13例患者因拔牙引起感染、17例患者出现上呼吸道感染、17例患者有全身类流感综合征或腹泻、发热等症状。患者发生急性脊髓炎后表现出不同程度的截瘫、感觉障碍以及括约肌功能障碍。治疗组患者治疗总有效率为91.3%;对照组患者为66.7%。治疗组患者的治疗总有效率明显高于对照组,差异具有统计学意义(P<0.05)。结论选用甲基强的松龙治疗急性脊髓炎患者具有更加理想的临床疗效,疗效确切可靠,临床应用价值高
Objective To study the clinical characteristics of acute myelitis and the effect of hormone therapy. Methods The clinical data of 47 patients with acute myelitis were retrospectively analyzed, and the clinical features of acute myelitis were summarized. The patients were divided into treatment group (23 cases) and control group (24 cases) according to different medication. The patients in the treatment group were treated with methylprednisolone, the patients in the control group were treated with dexamethasone, and the clinical effects of the two groups were analyzed. Results The prevalence of infection was common in patients before onset. Thirteen patients had upper extremity infection due to tooth extraction, 17 patients had systemic respiratory syndrome, or diarrhea and fever. Patients with acute myelitis showed varying degrees of paraplegia, sensory disturbances and sphincter dysfunction. The total effective rate was 91.3% in the treatment group and 66.7% in the control group. The total effective rate of treatment group was significantly higher than that of control group, the difference was statistically significant (P <0.05). Conclusion The use of methylprednisolone in the treatment of acute myelitis patients with more ideal clinical efficacy, the effect is reliable, clinical application of high value