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本文通过对43例慢性乙型肝炎的肝穿组织进行临床病理和超微病理检查(其中慢性迁延性肝炎6例,慢性活动性肝炎35例,肝炎后肝硬化2例),全部病例均做了乙肝病毒血清学检测和肝功化验,18例做了免疫电镜观察。探索慢性乙型肝炎病人的临床表现,肝组织病理形态和超微病理之间的关系。在慢性乙型肝炎的病程中,细胞器和细胞核的病变比较广泛,各型间各有重迭,但各有重点。慢性迁延性肝炎以单个肝细胞变性为主,主重表现为细胞核和细胞器的变性。慢性乙型迁延性肝炎的肝组织改变以肝细胞核变形,滑面内质网增生扩张, 单个肝细胞变性为主,个别病例狄氏间隙有胶原纤维增生。慢性
In this paper, 43 cases of chronic hepatitis B through the liver biopsy and pathological examination (including chronic persistent hepatitis in 6 cases, 35 cases of chronic active hepatitis, cirrhosis in 2 cases), all cases were done Hepatitis B virus serological tests and liver function tests, 18 cases of immunoelectron microscopy. To explore the clinical manifestations of patients with chronic hepatitis B, the relationship between the pathological morphology of liver tissue and ultrastructural pathology. In the course of chronic hepatitis B, the lesions of organelles and nuclei are more extensive, with overlapping between different types, but each has its own focus. Chronic persistent hepatitis with a single degeneration of liver cells, the main performance of the nuclear and organelles degeneration. Chronic B cirrhosis of liver tissue changes in liver cell nuclear deformation, sliding surface endoplasmic reticulum hyperplasia and expansion, the main single degeneration of liver cells, individual cases of Dick’s gap collagen fibers. Chronic