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大肠腺瘤是起源于肠上皮的良性肿瘤,属肠息肉的一种,如不正规处理及复诊,日久易复发甚至癌变。目前认为大肠癌的发生一般经历正常上皮-腺瘤-癌序列过程~([1]),而从正常黏膜发展到腺瘤再到癌变一般需要10年左右~([2]),且这期间常伴随相关蛋白因子的变化。近年来肠息肉的研究在遗传学、表观遗传学、免疫学和分子生物学发生机制上取得了巨大进展和成就,阐述了多种基因和细胞因子与肠息肉和癌变之间的联系,对大肠腺瘤及早期肠癌诊断、
Colorectal adenoma is a benign tumor originated in the intestinal epithelium, is a kind of intestinal polyps, such as irregular treatment and referral, easy to relapse or even cancer. At present, the occurrence of colorectal cancer is generally undergone normal epithelial-adenoma-cancer sequence ~ ([1]), while it takes about 10 years ~ ([2]) to develop from normal mucosa to adenoma to cancer. Often accompanied by changes in the relevant protein factors. In recent years, the study of intestinal polyps has made tremendous progress and achievements in the mechanisms of genetics, epigenetics, immunology and molecular biology, and elucidated the links between various genes and cytokines and intestinal polyps and carcinogenesis. Colorectal adenoma and early diagnosis of intestinal cancer,