血管紧张素Ⅱ有促进细胞生长、增殖的作用。该作用主要由血管紧张素Ⅱ的Ⅰ型受体介导。研究揭示其受体后的信号转导存在两种主要径路，即ＭＡＰＫｓ径路和ＪＡＫ－ＳＴＡＴ径路。ＡｎｇⅡ激活ＭＡＰＫｓ可能通过活化Ｒａｓ途径和ＰＫＣ径路；Ｓｒｃ家族可能参与了ＡｎｇⅡ激活ＪＡＫ－ＳＴＡＴ径路 Angiotensin II can promote cell growth and proliferation. This effect is mainly mediated by angiotensin II type I receptors. Research reveals that there are two main pathways for signal transduction after its receptor, MAPKs pathway and JAK-STAT pathway. Activation of MAPKs by AngⅡis possible through activation of Ras pathway and PKC pathway; Src family may be involved in AngⅡactivation of JAK-STAT pathway