近年来肺部疾病发病率不断增高,如哮喘、慢性阻塞性肺疾病(COPD)、肺囊性纤维化等。根据WHO相关数据显示,全球有近6500万人是中重度的COPD患者,超过23500万人为哮喘患者,并且大部分为儿童。肺功能检测(PFT)仍是目前诊断COPD金标准,但对其早期诊断不敏感,并且不能提供肺结构定位信息。肺部X线摄影仅得到肺结构信息。多层螺旋CT虽能提供肺功能信息,但对COPD早期诊 In recent years, the incidence of pulmonary diseases continues to increase, such as asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis and so on. According to WHO data, there are nearly 65 million people with moderate-to-severe COPD in the world, more than 235 million people with asthma and most of them children. Pulmonary function testing (PFT) is still the gold standard for the diagnosis of COPD, but it is not sensitive to its early diagnosis and does not provide information on lung structure localization. Pulmonary radiography only obtains lung structure information. Although MSCT can provide information on pulmonary function, early diagnosis of COPD