PPARδ作为调节糖、脂代谢重要的细胞核受体,不仅在肥胖的发生过程中起着重要作用,而且近年来研究显示其在提高耐力运动能力,促进肌纤维转变中发挥调控作用。大多数研究认为,有氧运动对骨骼肌PPARδm RNA和蛋白表达提高,而对于诱导肌纤维类型转化则存在争议。 As an important nuclear receptor that regulates the metabolism of glucose and lipid, PPARδ not only plays an important role in the pathogenesis of obesity, but also has been shown in recent years that PPARδ plays a regulatory role in improving endurance exercise capacity and promoting muscle fiber changes. Most studies suggest that aerobic exercise on skeletal muscle PPARδmRNA and protein expression increased, while the type of muscle fiber induced conversion is controversial.