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目的了解现阶段不同年龄阶段育龄期女性人群丙型肝炎病毒感染状况及流行特征。方法采用酶联免疫吸附试验(ELISA)检测本院2012年1月-2013年10月间68 125例育龄期女性丙型肝炎病毒感染状况。结果共筛查出抗-HCV抗体阳性者198例,阳性率为0.29%,16岁~19岁组、20岁~24岁组、25岁~29岁组、30岁~34岁组、35岁~39岁组、40岁~44岁组及45岁~49岁组阳性率分别为0.14%、0.15%、0.12%、0.21%、0.52%、0.71%和1.54%,不同年龄段育龄期女性抗-HCV抗体阳性率比较,差异有统计学意义(χ2=211.4,P<0.001)。城市与农村人群及门诊与住院人群相比阳性率差异均无统计学意义(P>0.05)。结论与男性及其他年龄阶段的女性人群相比,育龄期女性丙型肝炎病毒感染率呈现较低水平,不同年龄阶段的育龄期女性感染率亦存在差异。
Objective To understand the prevalence and epidemiological characteristics of hepatitis C virus in women of childbearing age in different age groups at the present stage. Methods The infection status of hepatitis C virus (HCV) in 68 125 women of childbearing age from January 2012 to October 2013 in our hospital was detected by enzyme-linked immunosorbent assay (ELISA). Results A total of 198 cases of anti-HCV antibodies were screened, the positive rate was 0.29%, 16 to 19 years old group, 20 to 24 years old group, 25 to 29 years old group, 30 to 34 years old group, 35 years old The positive rates of ~ 39 years old group, 40 ~ 44 years old group and 45 ~ 49 years old group were 0.14%, 0.15%, 0.12%, 0.21%, 0.52%, 0.71% and 1.54% -HCV antibody positive rate, the difference was statistically significant (χ2 = 211.4, P <0.001). There was no significant difference in the positive rates of urban and rural populations and outpatients and inpatients (P> 0.05). Conclusions Compared with female and other age groups, the infection rate of hepatitis C virus in childbearing women shows a low level. There are also differences in the infection rates among women of childbearing age in different age groups.