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目的：了解我院住院患者抗菌类药物临床应用情况，分析存在的问题。方法对我院2012年6月21日000-2400住院患者采用横断面方法调查抗菌药物的使用情况、DDDs值、病原微生物送检率，并对其进行分析。结果住院患者768例中有1274例使用抗菌药物，平均使用率为48.98%；抗细菌药物中，使用频率占前3位的依次为头孢菌素类(57.97%，其中第2、3代头孢菌素占49.64%)、氟喹诺酮类(28.68%)和青霉素类(13.35%)；有401例微生物送检，病原学送检率52.21%。结论我院抗菌药物使用率符合卫生部规定要求，但外科系统使用率较高，预防用药送检率较低，存在盲目用药的现象，需进一步规范抗菌药物的使用规范。“,”Objective To investigate the clinical application of antimicrobial agents for inpatients in our hospital. Methods A cross-section investigation method was carried out and analyzed the the utilization of antimicrobial agents, DDDs, The total rate of pathogens sent for etiological examination for all the inpatients within a day. Results Among the total 2601 inpatients investigated, 1274 cases used antibiotics, The average utilization rate was 48.98%; Among the antibacterial drugs, utilization rate from high to low was Cephalosporins(57.97%), fluoroquinolone 28.68% and penicillin 13.35%; There are 984 cases were sent for pathogens etiological examination, the rate of etiologic test was37.83%. Conclusion The rate of antibiotic use is Conform to the standard of Ministry of Health in China, but the utilization rate in the surgery was on the high side, the total rate of pathogens sent for etiological examination in Preventive medicine was low, which exist the phenomenon of using drug blindly and it is need to enhance the specification of using antimicrobial drugs.